Preston MacDougall<p><span class="h-card" translate="no"><a href="https://mastodon.social/@gutenberg_org" class="u-url mention" rel="nofollow noopener" target="_blank">@<span>gutenberg_org</span></a></span> With regard to Dr. Frankenstein’s monster and the history of <a href="https://mstdn.science/tags/chemistry" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>chemistry</span></a> in <a href="https://mstdn.science/tags/biology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>biology</span></a> , here’s a flashback: “Chemical Eye 👁️ on Synthetic Biology”, which was fittingly published in “The Exquisite Corpse”! <a href="http://www.corpse.org/index.php?option=com_content&task=view&id=312&Itemid=57" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">http://www.</span><span class="ellipsis">corpse.org/index.php?option=co</span><span class="invisible">m_content&task=view&id=312&Itemid=57</span></a> </p><p><a href="https://mstdn.science/tags/SynBio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>SynBio</span></a> is <a href="https://mstdn.science/tags/ChemBio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ChemBio</span></a>. 🧪 👉 🧬 👉 🧫 👉 🦠</p>
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#synbio
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JIPB<p>Synthetic biology-based <a href="https://mstdn.science/tags/biofortification" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>biofortification</span></a> of crop plants may be the key to addressing hidden <a href="https://mstdn.science/tags/hunger" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>hunger</span></a> caused by chronic <a href="https://mstdn.science/tags/micronutrient" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>micronutrient</span></a> deficiencies, which affect billions of people. Learn more in this <a href="https://mstdn.science/tags/OpenAccess" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>OpenAccess</span></a> mini-review!<br><a href="https://doi.org/10.1111/jipb.13934" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="">doi.org/10.1111/jipb.13934</span><span class="invisible"></span></a> <br> <a href="https://mstdn.science/tags/PlantScience" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>PlantScience</span></a> <a href="https://mstdn.science/tags/SynBio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>SynBio</span></a> 🔓 <a href="https://mstdn.science/tags/botany" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>botany</span></a></p>
James Hawley, PhD<p>An old friend of mine has a blog about <a href="https://scholar.social/tags/synBio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>synBio</span></a>, <a href="https://scholar.social/tags/genomics" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>genomics</span></a>, and <a href="https://scholar.social/tags/biology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>biology</span></a>. Here's the first post in a series on genome sequencing technology:</p><p><a href="https://editlife.substack.com/p/part-1-the-dna-sequencing-arms-race" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">editlife.substack.com/p/part-1</span><span class="invisible">-the-dna-sequencing-arms-race</span></a></p>
Alexander J. Stein<p>Scientists found a way to clean up <a href="https://mastodon.world/tags/methylmercury" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>methylmercury</span></a>, a dangerous pollutant that builds up in our <a href="https://mastodon.world/tags/environment" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>environment</span></a> due to human activities. Fish & flies can be engineered to break down this form of <a href="https://mastodon.world/tags/mercury" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>mercury</span></a> and remove it from their bodies as a less harmful gas, tackling related <a href="https://mastodon.world/tags/pollution" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>pollution</span></a> & <a href="https://mastodon.world/tags/foodsafety" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>foodsafety</span></a> issues. Species at the top of <a href="https://mastodon.world/tags/foodwebs" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>foodwebs</span></a>, incl. humans, can accumulate <a href="https://mastodon.world/tags/mercury" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>mercury</span></a> at levels that harm neural & reproductive health: <a href="https://lighthouse.mq.edu.au/article/february-2025/scientists-engineer-fish-and-flies-to-clean-up-toxic-mercury" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">lighthouse.mq.edu.au/article/f</span><span class="invisible">ebruary-2025/scientists-engineer-fish-and-flies-to-clean-up-toxic-mercury</span></a> <a href="https://mastodon.world/tags/health" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>health</span></a> <a href="https://mastodon.world/tags/synbio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>synbio</span></a></p>
Alexander J. Stein<p>To secure crop production in the face of <a href="https://mastodon.world/tags/climatechange" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>climatechange</span></a>, holistic solutions are needed, which involve a combination of <a href="https://mastodon.world/tags/plantbreeding" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>plantbreeding</span></a>, transgenesis & <a href="https://mastodon.world/tags/geneediting" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>geneediting</span></a>, as well as emerging <a href="https://mastodon.world/tags/syntheticbiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>syntheticbiology</span></a> tools that increase the precision & rate of crop improvement: <a href="https://doi.org/10.1016/j.tplants.2024.11.001" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">doi.org/10.1016/j.tplants.2024</span><span class="invisible">.11.001</span></a> <a href="https://mastodon.world/tags/synbio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>synbio</span></a></p>
Nonya Bidniss :CIAverified:<p>Meet Evo, the DNA-trained AI that creates genomes from scratch; ChatGPT-like model learns on its own to devise new proteins and genetic sequences</p><p>"In theory, malicious users could exploit a model like Evo to design a biological weapon, Hie says, so the researchers banished from the AI’s training set sequences from any viruses that attack humans or other eukaryotes, the organisms whose cells boast nuclei." </p><p>I'm sure that's 100% effective in a system that "hallucinates" by design. Reminds me of a research project from years ago, this scientist was making a database of genetic sequences that never occur in nature, thereby they would be assumed incompatible with life. <a href="https://infosec.exchange/tags/synbio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>synbio</span></a> <a href="https://infosec.exchange/tags/AI" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>AI</span></a> <a href="https://www.science.org/content/article/meet-evo-dna-trained-ai-creates-genomes-scratch" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">science.org/content/article/me</span><span class="invisible">et-evo-dna-trained-ai-creates-genomes-scratch</span></a></p>
Virgile Andreani<p>The strangest result I have seen recently, was today in lab meeting, from this article that we were discussing: <a href="https://www.nature.com/articles/s41589-021-00927-y" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">nature.com/articles/s41589-021</span><span class="invisible">-00927-y</span></a></p><p>Retrons are weird hybrid DNA-RNA structures, that include a characteristic "hairpin" structure such as in the picture.<br>In this study, they wanted to understand how the size of this hairpin influences the production of the retron.</p><p>1/2</p><p><a href="https://fosstodon.org/tags/JournalClub" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>JournalClub</span></a> <a href="https://fosstodon.org/tags/SyntheticBiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>SyntheticBiology</span></a> <a href="https://fosstodon.org/tags/synbio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>synbio</span></a></p>
idw_online<p>Ein Team @Bode_Lab @mpi_Marburg und Michael Groll @TU_Muenchen entwickelte mittels <a href="https://idw-online.social/tags/NRPS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>NRPS</span></a> Engineering einen selektiveren Hemmstoff für das Immunoproteasom - Potenzial für künftige Autoimmun-Therapien <a href="https://idw-online.social/tags/Synbio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Synbio</span></a> <a href="https://idw-online.social/tags/Medizin" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Medizin</span></a> <a href="https://idw-online.social/tags/Autoimmunkrankheiten" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Autoimmunkrankheiten</span></a><br><a href="https://nachrichten.idw-online.de/2024/08/16/hybride-pfeilspitze-gegen-autoimmunerkrankungen" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">nachrichten.idw-online.de/2024</span><span class="invisible">/08/16/hybride-pfeilspitze-gegen-autoimmunerkrankungen</span></a></p>
idw_online<p>Ein erster Schritt zu selbsterhaltenden zellfreien <a href="https://idw-online.social/tags/synbio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>synbio</span></a> Systemen für nachhaltige <a href="https://idw-online.social/tags/Biotechnologie" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Biotechnologie</span></a> 🧪: @simone_giaveri @erblabs @mpi_marburg verbindet erstmals in vitro einen synthetischen Stoffwechsel mit Genexpression - mit <a href="https://idw-online.social/tags/CO2" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>CO2</span></a> als Rohstoff. <br><a href="https://nachrichten.idw-online.de/2024/07/11/ein-motor-fuer-den-zellfreien-stoffwechsel" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">nachrichten.idw-online.de/2024</span><span class="invisible">/07/11/ein-motor-fuer-den-zellfreien-stoffwechsel</span></a></p>
Mattias Malaguti<p><a href="https://biologists.social/tags/Introduction" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Introduction</span></a></p><p>Hello! </p><p>I'm a synthetic developmental biologist at The University of Edinburgh.</p><p>I'm interested in understanding how cells influence their neighbours in mammalian models of <a href="https://biologists.social/tags/DevBio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>DevBio</span></a> and disease.</p><p>I use <a href="https://biologists.social/tags/SynBio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>SynBio</span></a> to identify neighbours of cells of interest (e.g. healthy neighbours of mutant cells), and to engineer cell behaviour in response to these interactions.</p><p>I do this in pluripotent <a href="https://biologists.social/tags/StemCells" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>StemCells</span></a> and their derivatives.</p><p>I look forward to keeping up with everyone's cool research!</p>
Tim<p>Allow me to reintroduce myself on this pachyderm app.</p><p>I sell open source synthetic biology software and open source synthetic biology software accessories.</p><p><a href="https://github.com/TimothyStiles/poly" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="">github.com/TimothyStiles/poly</span><span class="invisible"></span></a></p><p><a href="https://genomic.social/tags/introduction" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>introduction</span></a> <a href="https://genomic.social/tags/synbio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>synbio</span></a> <a href="https://genomic.social/tags/syntheticbiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>syntheticbiology</span></a> <a href="https://genomic.social/tags/molecularbiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>molecularbiology</span></a></p>
Anirban Mahapatra<p>Hello, everyone! Ani here. I trained as a microbiologist. In the lab I worked on methanogens, genetic code expansion, and inserting unnatural amino acids into proteins. </p><p>I’ve spent the past 15 years helping scientists grow communities and journals at professional societies. But I still have a hard time explaining just what it is that I do (there are some links in my bio that might help). My posts may be unrelated to my work too. 😆 </p><p><a href="https://fediscience.org/tags/introduction" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>introduction</span></a> <a href="https://fediscience.org/tags/microbiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>microbiology</span></a> <a href="https://fediscience.org/tags/science" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>science</span></a> <a href="https://fediscience.org/tags/synbio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>synbio</span></a> <a href="https://fediscience.org/tags/chemistry" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>chemistry</span></a></p>
Alisson Gontijo<p><a href="https://drosophila.social/tags/introduction" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>introduction</span></a> <a href="https://drosophila.social/tags/ScienceMastodon" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ScienceMastodon</span></a><br>Hello!<br>I am an assistant professor at the Faculdade de Ciências of the University of Lisbon & <a href="https://drosophila.social/tags/research" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>research</span></a> group leader at Nova Medical School, Lisbon, <a href="https://drosophila.social/tags/Portugal" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Portugal</span></a>.<br>
<br>Our lab is interested in <a href="https://drosophila.social/tags/genetics" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>genetics</span></a>, <a href="https://drosophila.social/tags/physiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>physiology</span></a>, <a href="https://drosophila.social/tags/neurobiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>neurobiology</span></a>, <a href="https://drosophila.social/tags/behavior" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>behavior</span></a>, <a href="https://drosophila.social/tags/development" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>development</span></a>, <a href="https://drosophila.social/tags/evolution" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>evolution</span></a>, <a href="https://drosophila.social/tags/synbio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>synbio</span></a>, <a href="https://drosophila.social/tags/bioengineering" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>bioengineering</span></a>, <a href="https://drosophila.social/tags/diseasemodelling" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>diseasemodelling</span></a>, and we use <a href="https://drosophila.social/tags/Drosophila" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Drosophila</span></a>, <a href="https://drosophila.social/tags/stemcells" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>stemcells</span></a>, and <a href="https://drosophila.social/tags/computationalbiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>computationalbiology</span></a> approaches.</p><p>I am interested in everything <a href="https://drosophila.social/tags/Science" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Science</span></a>, <a href="https://drosophila.social/tags/History" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>History</span></a>, <a href="https://drosophila.social/tags/Politics" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Politics</span></a>, <a href="https://drosophila.social/tags/Music" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Music</span></a>, and other stuff.</p>
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