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Benjamin Carr, Ph.D. 👨🏻‍💻🧬<p>A dangerous <a href="https://hachyderm.io/tags/Ecoli" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Ecoli</span></a> strain has emerged; a small <a href="https://hachyderm.io/tags/mutation" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>mutation</span></a> may explain its rise<br>A sweeping genetic analysis by researchers at <a href="https://hachyderm.io/tags/CDC" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>CDC</span></a> suggests a tiny mutation in one of the <a href="https://hachyderm.io/tags/bacteria" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>bacteria</span></a>'s molecular weapons may be behind the strain's rise. The mutation the CDC researchers found was in one of these <a href="https://hachyderm.io/tags/T3SS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>T3SS</span></a> effectors, a protein called <a href="https://hachyderm.io/tags/EspW" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>EspW</span></a>. The CDC researchers suggest this could help E. coli when it's on <a href="https://hachyderm.io/tags/lettuce" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>lettuce</span></a> and other <a href="https://hachyderm.io/tags/produce" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>produce</span></a>. <br><a href="https://arstechnica.com/health/2025/05/a-dangerous-e-coli-strain-has-emerged-a-small-mutation-may-explain-its-rise/" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">arstechnica.com/health/2025/05</span><span class="invisible">/a-dangerous-e-coli-strain-has-emerged-a-small-mutation-may-explain-its-rise/</span></a></p>
PLOS Biology<p>This study uses a <a href="https://fediscience.org/tags/FluidFM" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>FluidFM</span></a>-based injection approach to show that establishment of a <a href="https://fediscience.org/tags/Salmonella" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Salmonella</span></a> replicative niche in the cytosol of enteroid cells (when uncoupled from invasion) does not require <a href="https://fediscience.org/tags/flagellin" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>flagellin</span></a> or <a href="https://fediscience.org/tags/T3SS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>T3SS</span></a> effectors <a href="https://fediscience.org/tags/PLOSBiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>PLOSBiology</span></a> @Microbio_ETH <a href="https://plos.io/3UBBUhz" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="">plos.io/3UBBUhz</span><span class="invisible"></span></a></p>