At our #DataScience @univienna Talk next Monday 5 May, Thomas Rattei explores how #MachineLearning predicts microbial traits from genomic data: protein families as features, #NeuralNetworks for practical phenotype prediction #Genomics #Microbiology #DSHQ
https://datascience.univie.ac.at/events/talks-detail/news/thomas-rattei-genome-based-prediction-of-microbial-traits/

https://www.europesays.com/uk/58357/ Largest study identifies new genetic targets for osteoarthritis treatment #Arthritis #Drugs #Genes #Genetic #Genetics #Genomics #Medicine #Musculoskeletal #Orthopedic #Osteoarthritis #pain #Research #Science #UK #UnitedKingdom

https://www.europesays.com/uk/53123/ Scientists uncover the genetic landscape of the apple genus #Agriculture #Apple #breeding #Disease #Genetics #Genomics #Research #Science #UK #UnitedKingdom

https://www.europesays.com/uk/52123/ Advances in single-cell DNA sequencing enable insights into human somatic mosaicism #Agriculture #AnimalGeneticsAndGenomics #Biomedicine #CancerResearch #DNASequencing #GeneFunction #general #GeneticVariation #Genetics #Genomics #HumanGenetics #Mutation #Science #UK #UnitedKingdom

GHGA Data Portal 3.0 is live!
A major update with:
Sleek new UI (Angular)
Smarter role management
Usage analytics
Stronger backend stability

Learn more: https://www.ghga.de/news/detail/ghga-data-portal-update-release-30

NHS England in Talks on UK Biobank Access to GP Patient Data https://www.byteseu.com/950722/ #ArtificialIntelligence #AtrialFibrillation;AF;Afib;AFib;Afib;AFib;AtrialFib;AtrialFibrillation(AF);AtrialFibrillation(AFib) #BiologicTherapy #Biologics #depression #Genomics;GenomicMedicine #GreatBritain #NationalHealthService #NHS #PrimaryCare #UK #UKNationalHealthService #UKNHS #UKSiteContent;UnitedKingdomSiteContent #UnitedKingdom #UnitedKingdomNationalHealthService

Our research is now supported by a 2024 Simons Foundation Autism Research Initiative (SFARI) Pilot Award, co-funded by the Nancy Lurie Marks Family Foundation (NLMFF). I am grateful to both SFARI and NLMFF for investing in high-risk, high-reward science to advance understanding of autism spectrum disorders (ASD) and neurodevelopmental disorders.

The project will explore how mutations in chromatin regulators ASH1L and SETBP1 impair their crucial role in guiding the development of GABAergic neurons—key cells maintaining the brain’s balance between excitation and inhibition. Disruptions in this process are strongly linked to ASD, but the molecular pathways remain poorly understood.

By integrating genomic, proteomic, and functional approaches, we aim to reveal how these enzymes regulate gene activity during inhibitory neuron development and how their dysfunction contributes to ASD.

Official announcements:
SFARI: https://www.sfari.org/2025/04/08/announcing-the-recipients-of-the-2024-pilot-and-pilot-progression-awards/
NLMFF: https://www.nlmfoundation.org/grant/epigenetic-regulators-ash1l-and-setbp1-in-gabaergic-neuron-development-and-asd/

I wanna get back into software dev (just as a hobby for now), and it would be super cool to contribute to open source creative coding software (strudel, hydra, etc.) or something biotech/‘omics related, as I studied that at uni, but I just have no clue whatsoever where to start…

If anyone out there has any tips that would be greatly appreciated

New study by Chan et al. reveals the evolutionary dynamics of self-splicing introns in mitochondrial genomes of Epichloë fungi. Results support rapid intron loss and evolution of homing suppressors.

Link: https://doi.org/10.1093/molbev/msaf076

Anyone else finding the sequencing costs appear to be getting more expensive rather then continuing to decline. I'm thinking its likely related to inflation, wages and current US uncertainty...? oh and Illumina and alike only delivering true reduced cost/GB on large scale flowcells, which aren't suitable for many small to medium size projects...
#genomics #bioinformatics

GHGA Retreat 2025 – Day 3: Focused workstream sessions underway! Teams are aligning on key topics like architecture, data stewardship, genomDE model project, workflows, and outreach to drive GHGA forward. It's a rare opportunity with all team members from different workstreams in one room. #GHGAretreat #TeamAlignment #Genomics #Collaboration #genomDE

The GenomDE Symposium 2025 is jointly organized by TMF, @bfarm_de @ghga and @deNBI Expect exciting talks and discussions on current topics in #genomics and #bioinformatics .
10-11 July
Berlin
For more information see: https://www.denbi.de/de-nbi-events/1879-4th-genomde-symposium

GHGA Retreat 2025 – Day 2: Deep-dive workshops underway at Kloster Schöntal! We’re aligning on the GHGA Data Portal roadmap, exploring community-driven projects, and refining plans for SPEs and patient communication.

GHGA Retreat – Day 1 at Kloster Schöntal kicked off with exciting discussions on a wide range of topics! From data portals to international connectivity (#FEGA, #ELIXIR, #EOSC), legal challenges, patient communication, and training plans, GHGA 2 is taking shape across all fronts. Perspectives from data producers and data hubs, along with workflow use cases, rounded off a fantastic first session. #GHGA #GHGAretreat #Genomics #OpenScience #Collaboration

How #genome-wide sequence divergence maps to species status https://www.pnas.org/doi/10.1073/pnas.2319389122 #biodiversity #genomics

#Genetic data site #openSNP to close and delete data over #privacy concerns
openSNP, a platform for sharing genetic and phenotypic data, will shut down, and delete all user submissions over privacy concerns and risk of misuse by authoritarian governments.
Announced earlier this week by co-founder Bastian Greshake Tzovaras, who expressed concerns about how personal #genomics data is subject to abuse today and how fundamentally landscape has changed over the last 14 years.
https://www.bleepingcomputer.com/news/security/genetic-data-site-opensnp-to-close-and-delete-data-over-privacy-concerns/

The European Reference Genome Atlas (ERGA) is a community initiative coordinating the production of a reference #genome for all eukaryotic species in Europe. https://en.wikipedia.org/wiki/European_Reference_Genome_Atlas #Biodiversity #Genomics

#Genetics #Genomics #Cancer #Academia #AcademicChatter

Interested in cancer genetics? Don't want to fly somewhere to here about it? Next week the American Society of Human Genetics is having an online-only digital symposium on cancer genetics.

https://www.ashg.org/product/2025-spring-symposium-emerging-frontiers-in-cancer-genetics/

I think it's also worth up to 6 #CME credits if you do continuing medical education.

We have a 4-year PhD position available in the Slotte lab at Stockholm University, to investigate genomic signatures of selection associated with pollination mode shifts.
Full ad: https://su.varbi.com/en/what:job/jobID:805144/where:4/
Apply by April 22, 2025 via the University application portal. Please repost! #stockholm #evolgen #evolution #genomics #phdPosition