A Gene Editing Strategy to Repair Huntington's Defects
"A lot more studies would be needed before we can know if disrupting these repeats with a base editor could be a viable therapeutic strategy to treat patients. But being able to illuminate the biological consequences of interrupted repeats is a really useful and important milestone," explained senior study author Dr David Liu.
#CRISPR #genetics #research #biology #biotechnology #science #Huntingtons
I'd like to read more about DNA & CRISPR. The origins, the background story, but also how CRISPR works etc.
Does anybody know which book I should read? There are multiple books on the topic & it's hard for a layman to choose from.
My background is in IT & (Interaction) Design.
https://www.europesays.com/uk/149057/ Spiders’ genes have been modified to produce glowing silk – a scientific sensation #breakthrough #Change #considered #crispr #fiber #First #Genetic #Genetics #major #medical #Natural #perfect #Professor #properties #researchers #Science #Scientific #spider #Spiders #study #Technology #UK #UnitedKingdom
New #CRISPR technology could help repair damaged neurons https://news.stanford.edu/stories/2025/05/crispr-technology-neurodegenerative-diseases-als-spinal-muscular-atrophy
This is an example of what is being eliminated as Republicans in Washington, DC and this administration make catastrophic cuts to scientific research (among other things) to provide tax cuts to and curry favor with billionaires:
"World’s first patient treated with personalized CRISPR gene editing therapy at Children’s Hospital of Philadelphia"
https://www.pennmedicine.org/News/worlds-first-patient-treated-with-personalized-crispr-therapy
#ScienceMatters #science #CRISPR #antiscience #DOGE
What are the best ways these days for folks without institutional accounts to read recent journal articles that aren't open access? It's so disappointing not to be able to read papers like this that are all over the media.
For this one I even tried to make the free NEJM account but it didn't work.
Please don't say to email the authors.
Dive into the groundbreaking world of CRISPR-Cas9 with Jennifer Doudna on Cleo Abram's channel! 
This video breaks down how we can now edit our own genes. Mind-blowing stuff!
Baby Is Healed With World’s First Personalized Gene-Editing Treatment.
The technique used on a 9½-month-old boy with a rare condition has the potential to help people with thousands of other uncommon genetic diseases.
https://www.nytimes.com/2025/05/15/health/gene-editing-personalized-rare-disorders.html?unlocked_article_code=1.Hk8.wt5y.1chNUwxx815P&smid=url-share&fbclid=IwY2xjawKUeChleHRuA2FlbQIxMABicmlkETBpcWpnVEtiZnJ0S3hTclJwAR4DmWeeHkLifw6xpi6qz_UxwoMN8cWOUSF5yPLITApHCR_Z8B-bCuZw8Q8A7A_aem_BZHhad4Od2mkYpN_1s0icQ #genetics #CRISPR #genetherapy
(Just another example of why we should treasure our researchers and scientists)
Good news from @npr, as shared by our @ScienceDesk. A baby born in Philadelphia last August with a life-threatening genetic disorder was successfully treated with a gene-editing infusion developed using CRISPR technology. His genetic defect appears to have been fixed, at least partially reversing his condition.
holy moly! a baby born with a rare and dangerous genetic disease is growing and thriving after getting an experimental gene editing treatment made just for them:
https://www.cbc.ca/news/health/gene-therapy-baby-pennsylvania-1.7536105
When KJ Muldoon was born at Children's Hospital of Philadelphia (CHOP) in August, doctors noticed that he was lethargic. They carried out tests that revealed he had a genetic metabolic disorder that leads to the buildup of ammonia and can cause brain damage and death. Gene sequencing helped them determine the exact location of the error that led to him being unable to make a vital enzyme. This allowed doctors to use CRISPR technology to create a treatment tailored specifically towards his unique mutation. After three infusions containing billions of gene editors, his defect appears to have been corrected and his condition, at least partially reversed. "This is an important first step towards an entirely new type of personalized medicine. I think it's going to utterly transform the way we practice medicine, particularly in the area of rare diseases," says Dr. Kiran Musunuru, a professor for translational research at the University of Pennsylvania, who worked on KJ's case. See the @npr story at the first link. There's a link to the original article in the New England Journal of Medicine at the second link.
How great for this baby and this family. How sad about destroying the science infrastructure that enabled this.
Patentstreit um CRISPR: Wer hat die Genschere wirklich erfunden?
Das US-Berufungsgericht hat entschieden, dass der Patentstreit um die Gentechnik CRISPR neu aufgerollt werden muss. Es geht um Millionen und Ehre.
Der CRISPR-Patentstreit gehört zu den kompliziertesten Prozessen der jüngsten Zeit. Man verhandelt auf dem Niveau von Technologien wie der Dampfmaschine, dem Telefon, der Glühbirne oder dem Laser.
Meine Kollegin Alisa Pankau und ich haben lange über eine passende Überschrift für ihre News nachgedacht. Es flogen großartige - und vor allem auch witzige - Varianten hin und her. 
Letztlich haben wir uns für diese entschieden, denn - sind wir mal ehrlich - um eine Abwandlung des legendären Rambo-Zitates kam man hier nicht drum herum!
https://t3n.de/news/er-leuchtet-rot-forschende-spinnenfaden-1686832/
Spinnenseide fasziniert: Die Fäden sind unglaublich elastisch, wasserabweisend, sauerstoffdurchlässig und dazu noch biologisch abbaubar.
#India approved its first gene-edited rice varieties, signaling a shift to more #sustainable, high-performing crops. Unlike #GMOs, the new #rice lines, created using #CRISPR, rely on precise #geneediting to enhance resilience & #productivity to address new #climate realities: doi.org/10.1038/d441...
India approves first genome-ed...
USA lassen gentechnisch veränderte Schweine für den Verzehr zu
Gentechnisch veränderte Schweine, die resistent gegen ein gefährliches Virus sind, wurden in den USA für den Verzehr zugelassen. Welche Folgen hat das?
At any moment, and largely hidden from sight, bacteria and viruses are battling it out.
These skirmishes have inspired revolutionary technologies: Discoveries related to the #CRISPR-Cas system, for example, which allows bacteria to defend themselves from invading viruses, were recognized with a 2020 Nobel Prize.
New tech gleaned from this ongoing arms race includes potential antiviral medications and tricks for fighting bacteria, Amber Dance writes at Nature.
https://www.nature.com/articles/d41586-025-01065-4
The plan for #deregulation of plants derived from new #geneticengineering violates international law.
#NewGE #NGT #NewGeneticEngineering #CRISPR #biodiversity #biosafety
