PLOS Biology<p>What is the therapeutic potential of correcting mutations by base editing of the <a href="https://fediscience.org/tags/MitochondrialGenome" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>MitochondrialGenome</span></a>? This study shows that <a href="https://fediscience.org/tags/mitochondrial" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>mitochondrial</span></a> <a href="https://fediscience.org/tags/BaseEditing" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>BaseEditing</span></a> can indeed functionally create & correct mitochondrial pathogenic <a href="https://fediscience.org/tags/mutations" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>mutations</span></a> in patient-derived cells <span class="h-card" translate="no"><a href="https://fediscience.org/@PLOSBiology" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@<span>PLOSBiology</span></a></span> <a href="https://plos.io/3ZMa2K2" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://</span><span class="">plos.io/3ZMa2K2</span><span class="invisible"></span></a></p>