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@goatsarah Aged 10 (late C19), my grandmother's aunt went paddling and her feet were cut by a piece of tin. They became infected (I presume they developed gangrene). By the time she saw a doctor, the only solution was amputation. Both feet, on the kitchen table of the girl's house, without anaesthetic. Apparently, she could be heard screaming from outside the house.

It's besides the point, but they could've given her tourniquet anaesthesia as a non-pharmaceutical option.